Module Title:Biochemistry
Language of Instruction:English
Credits: 10
NFQ Level:7
Module Delivered In 2 programme(s)
Teaching & Learning Strategies: This module will be delivered via a two theory classes of one hour duration for thirty weeks and one four-hour practical every second week for twenty weeks for each group. Students may be required to access the material via Blackboard in advance of the class and practicals to encourage active learning. To consolidate lectures and practicals, students will be required to carry out assignments, take formative quizzes and multiple choice questions. Group and peer learning will be facilitated during the preparation of assignments and practicals. Any course-related issue or questions that may arise will be discussed at lectures. Students can contact lecturer outside of class hours to discuss formative feedback given on written reports and group project work. The practical component will: • allow students to develop the required technical competencies, attitudes and behaviours. • develop problem solving abilities and group skills. • promote deep learning via investigation of a problem, application of prior knowledge and analysis of results thus generating new knowledge. • promote timely submission of reports written in the standard format. • allow individual interaction with the lecturer.
Module Aim: The aim of this module is to expand the knowledge of biochemical processes, systems and structures.
Learning Outcomes
On successful completion of this module the learner should be able to:
LO1 Describe the synthesis, structure, function and interactions of major biomolecules.
LO2 Describe and elucidate the major metabolic pathways; explain how metabolism is controlled and metabolic diseases occur.
LO3 Demonstrate the application of biochemical processes.
LO4 Carry out a range of biochemical analysis with due regard to health and safety.
LO5 Develop individual and team based biochemical analysis skills
Pre-requisite learning
Module Recommendations

This is prior learning (or a practical skill) that is recommended before enrolment in this module.

No recommendations listed
Incompatible Modules
These are modules which have learning outcomes that are too similar to the learning outcomes of this module.
No incompatible modules listed
Co-requisite Modules
No Co-requisite modules listed
Requirements
This is prior learning (or a practical skill) that is mandatory before enrolment in this module is allowed.
Successful completion of year 2 or equivalent.
 

Module Content & Assessment

Indicative Content
Theory
Biomolecules and biomolecular synthesis, structure and function. Animal, plant and bacterial polysaccarides. Glycoproteins and glycolipids in membranes, energy stores and in membranes. Specialised lipids. Major enzyme groups and modes of action. Importance of cofactors including minerals and vitamins. Enzymology: reversible and irreversible inhibition. Ki. Allosteric enzymes.
Metabolism and metabolic disease:
Glycolysis and Gluconeogenesis: Review of both processes; What happens during periods of low oxygen; use of sugars other than glucose. Citric acid cycle: Review of the Citric Acid pathway; how it intersects with other metabolic pathways. Electron transport and ATP synthesis: obtaining energy from glucose. The pentose phosphate pathway and glycogen metabolism: Glucose 6-phosphate: the central component of the pentose phosphate pathway, glycogen metabolism. Regulation of carbohydrate pathways; interactions between anabolic and catabolic pathways, energy storage.
Photobiology
Biologically important interactions with light, Photosynthesis (light and dark phases), Biochemistry of the visual process.
Hormones.
The structure and function of hormones and their integration and regulation in mammalian metabolism. Metabolic disease.
Cholesterol biosynthesis.
Control and regulation. Lipid metabolism and regulation, Ketone bodies as fuel molecules.
Signal Transduction.
Signal transduction: G-Proteins, Adenylyl Cyclase Signaling Pathway, Inositol-Phospholipid Signaling Pathway, Receptor Tyrosine Kinases, Integration of metabolism.
Practical
Students will build on biochemical skills developed to date and apply these in areas such as adsorption, thin-layer chromatography of lipids, enzyme analysis, enzyme assays, protein analysis and identification. Electrophoresis, crude protein extraction and chromatography.
Assessment Breakdown%
Continuous Assessment10.00%
Practical40.00%
End of Module Formal Examination50.00%
Special Regulation
Students must achieve a minimum grade (35%) in both the practical/CA and final examination.
Continuous Assessment
Assessment Type Assessment Description Outcome addressed % of total Assessment Date
Other Multiple choice questions and short answer questions. 1,2,3 10.00 n/a
No Project
Practical
Assessment Type Assessment Description Outcome addressed % of total Assessment Date
Practical/Skills Evaluation Practical laboratory books 4,5 40.00 Every Week
End of Module Formal Examination
Assessment Type Assessment Description Outcome addressed % of total Assessment Date
Formal Exam No Description 1,2,3 50.00 End-of-Semester

ITCarlow reserves the right to alter the nature and timings of assessment

 

Module Workload

Workload: Full Time
Workload Type Frequency Average Weekly Learner Workload
Lecture 30 Weeks per Stage 2.00
Laboratory 30 Weeks per Stage 2.00
Estimated Learner Hours 30 Weeks per Stage 2.00
Total Hours 180.00
 

Module Delivered In

Programme Code Programme Semester Delivery
CW_SABTP_B Bachelor of Science (Honours) in Biosciences with Biopharmaceuticals 3 Mandatory
CW_SABFQ_D Bachelor of Science in Biosciences 3 Mandatory