This module will be delivered via three one-hour lectures for twelve weeks and two three-hour practicals for twelve weeks. Students may be required to access the material via College networks in advance of the class and practicals to encourage active learning. To consolidate lectures and practicals, students will normally be required to carry out assignments, give presentations and answer multiple choice questions. Group and peer learning will be facilitated during the preparation of assignments, presentations and practicals. Any course-related issue or questions that may arise will be discussed at lectures. Online demonstrations will illustrate the key concepts of the course and will be available throughout the year. Digital resources such as Youtube, Reusable learning objects and the National Digital Learning Repository will be used as practicable.
Module Aim:
To give the student an insight into the requirements of formulation and compounding in modern pharmaceutical industry.
Learning Outcomes
On successful completion of this module the learner should be able to:
LO1
Evaluate the procedures in drug production from synthesis to finished product manufacture.
LO2
Evaluate advanced methods used in preformulation screening of drugs and excipients
LO3
Evaluate and interpret the processes involved in drug manufacture and basic quality assurance
LO4
Interpret the principles underlying good manufacturing practices as applied to pharmaceutical industries
LO5
Evaluate the procedures of drug production from synthesis to finished product manufacture.
LO6
Develop analytical procedures for routine pharmaceutical analysis.
Pre-requisite learning
Module Recommendations
This is prior learning (or a practical skill) that is recommended before enrolment in this module.
No recommendations listed
Incompatible Modules
These are modules which have learning outcomes that are too similar to the learning outcomes of this module.
No incompatible modules listed
Co-requisite Modules
No Co-requisite modules listed
Requirements
This is prior learning (or a practical skill) that is mandatory before enrolment in this module is allowed.
No requirements listed
Module Content & Assessment
Indicative Content
Pharmaceutical Formulation
• Prepare standard pharmaceutical products from first principles
• Appreciate the critical importance of precise dosage: accurate weighing and volume delivery, sample preparation and reporting in the preparation and manufacture of medicines
• Source information in a practical way from pharmacopoiae and other sources
• Discuss the procedures in drug production from synthesis to finished product manufacture.
• Evaluate the methods used in preformulation screening of drugs and excipients
• Develop and test a range of products containing pharmaceutical actives.
• Explore the use of sustained-release drug-delivery vehicles
• Explain drug registration requirements.
• Evaluate and discuss processes involved in drug manufacture and basic quality assurance
• Explain the principles underlying good manufacturing practices as applied to pharmaceutical industries
• Understand the procedures in drug production from synthesis to finished product manufacture.
• Develop analytical procedures for routine pharmaceutical analysis.
• Understand drug registration requirements.
• Validate existing drug manufacturing plant and instrumentation
Assessment Breakdown
%
Continuous Assessment
10.00%
Practical
20.00%
End of Module Formal Examination
70.00%
Special Regulation
Students must achieve a minimum grade (35%) in both practical/CA and final exam.
Continuous Assessment
Assessment Type
Assessment Description
Outcome addressed
% of total
Assessment Date
Examination
Continuous assessment mid-term examinations
1,2,3,4,5
10.00
Week 8
No Project
Practical
Assessment Type
Assessment Description
Outcome addressed
% of total
Assessment Date
Practical/Skills Evaluation
Laboratory preparation, analysis
1,2,5,6
20.00
End-of-Semester
End of Module Formal Examination
Assessment Type
Assessment Description
Outcome addressed
% of total
Assessment Date
Formal Exam
Final written examination
1,4,5
70.00
End-of-Semester
SETU Carlow Campus reserves the right to alter the nature and timings of assessment