This module will be delivered via three one-hour lectures and two three-hour practicals per week. . Students may be required to carry out assignments, give presentations and take multiple choice questions. Independent learning will be facilitated during the preparation of assignments, presentations and practicals.
Module Aim:
To develop separation and extraction strategies in the analysis of drugs in pharmaceutical preparations
Learning Outcomes
On successful completion of this module the learner should be able to:
LO1
Develop spectroscopic and other methods in the principles of validation of an analytical method.
LO2
Validate the major extraction and separation techniques used in sample recovery
LO3
Explore the assay methods to determine contaminant degradation by-products using standard chromatographic techniques
LO4
Evaluate the methods used in the analysis of various drug delivery vehicles
Pre-requisite learning
Module Recommendations
This is prior learning (or a practical skill) that is recommended before enrolment in this module.
No recommendations listed
Incompatible Modules
These are modules which have learning outcomes that are too similar to the learning outcomes of this module.
No incompatible modules listed
Co-requisite Modules
No Co-requisite modules listed
Requirements
This is prior learning (or a practical skill) that is mandatory before enrolment in this module is allowed.
No requirements listed
Module Content & Assessment
Indicative Content
Assay Development
• Discuss the principles of validation of an analytical method.
• Evaluate the major extraction and separation techniques used in sample recovery
• Develop assay methods separating out drug and primary metabolites using standard chromatographic methods
• Explore the robustness of the methods in the analysis of sustained-release, multi-dose and other drug-delivery forms
Assessment Breakdown
%
Continuous Assessment
10.00%
Practical
30.00%
End of Module Formal Examination
60.00%
Special Regulation
Students must achieve a minimum grade (35%) in both practical/CA and final exam.
Continuous Assessment
Assessment Type
Assessment Description
Outcome addressed
% of total
Assessment Date
Case Studies
Regular written examinations to evaluate student understanding of course content
1,4
10.00
n/a
No Project
Practical
Assessment Type
Assessment Description
Outcome addressed
% of total
Assessment Date
Practical/Skills Evaluation
Solvent extraction, flocculation, Sep-pack® and pre-column separation. pKa separation.
2,3
30.00
n/a
End of Module Formal Examination
Assessment Type
Assessment Description
Outcome addressed
% of total
Assessment Date
Formal Exam
Final year evaluation
1,4
60.00
End-of-Semester
SETU Carlow Campus reserves the right to alter the nature and timings of assessment