Module Title: | Pharm Chemistry, Formulation and Compounding |
Language of Instruction: | English |
Module Delivered In |
No Programmes
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Teaching & Learning Strategies: |
The module will be delivered as two one-hour theory classes for thirty weeks and one three- hour practical class for fifteen weeks. Group and peer learning will be facilitated during the preparation of assignments and practicals. Any course-related issue or questions that may arise will be discussed at lectures. |
Module Aim: |
The aim of this module is to impart knowledge of fundamental chemistry and to provide practical training in this subject area with due regard to best practice and safety.
It also aims to give the student foundation level knowledge of the skills and competencies of formulation and compounding in the modern pharmacy.
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Learning Outcomes |
On successful completion of this module the learner should be able to: |
LO1 |
Interpret the basic concepts of atomic and molecular structures and bonding of simple chemicals and use the periodic table. |
LO2 |
Interpret the basic principles of solution chemistry. |
LO3 |
Understand the concepts of acidity and basicity and pH as they apply to biological systems. |
LO4 |
Perform the calculations involved in solution preparation. |
LO5 |
Perform designated practical exercises in the area of solution preparation with due regard to accuracy and precision, practical dexterity and good laboratory practice. |
LO6 |
Prepare simple pharmaceutical products from first principles |
LO7 |
Appreciate the critical importance of precise dosage: accurate weighing and volume delivery, sample preparation and reporting in the preparation and manufacture of medicines |
LO8 |
Source information in a practical way from pharmacopoiae and other sources |
LO9 |
Explain the principles underlying good manufacturing practices as applied to pharmaceutical industries. |
LO10 |
Handle drugs and their excipients with the requisite level of care with regard at all times to the health and safety of both the patient and pharmaceutical staff |
Pre-requisite learning |
Module Recommendations
This is prior learning (or a practical skill) that is recommended before enrolment in this module.
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No recommendations listed |
Incompatible Modules
These are modules which have learning outcomes that are too similar to the learning outcomes of this module. |
No incompatible modules listed |
Co-requisite Modules
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No Co-requisite modules listed |
Requirements
This is prior learning (or a practical skill) that is mandatory before enrolment in this module is allowed. |
No requirements listed |
Module Content & Assessment
Indicative Content |
Theory 1
Atoms, atomic structure, elements, compounds and mixtures.
The periodic table of the elements, molecules and bonding.
The Mole, molar mass and molar volume.
Concentration, molarity, normality and standard solutions.
Polarity of compounds and solvents.
Solutions and solubility. Concentrated, dilute, saturated and supersaturated solutions.
Precipitates, suspensions and colloids.
Acids, bases, buffers, the pH scale and indicators.
Introduction to organic chemistry, homologous series
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Theory 2
Structures of common pharmaceutical products: vitamins, analgesics, anti-inflammatory medicines and antibiotics.
Detergents and surfactants.
Drug classification. Pharmacopoeial monographs. The British Pharmacopoeia. The USP, Martindale, MIMS, etc.
Terms and acronyms. Basic pharmaceutical acronyms FDA, GMS, OTC, ICH, etc.
Liquid medicines. Structure of emulsions. Emollients.
Suppositories, sticks, gels.
Dispersed systems. Aerosols & suspensions.
Topical preparations. The structure and function of the skin, tooth and hair. Preparation of creams, emulsions and lotions. Ointments, pomades. Dentifrices.
Introduction to solid dosage forms. Tablets, capsules and other solid products.
Liquid preparations. Syrups and elixirs, linctuses. Advantages of delivery. Stability. Shelf-life.
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Practicals
The scheduled practicals will develop the following skills: Accuracy and precision in liquid measurement, standard solution preparation, titration, measurement of pH, effect of buffers, and analyses of common pharmaceutical products
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Assessment Breakdown | % |
Continuous Assessment | 20.00% |
Practical | 30.00% |
End of Module Formal Examination | 50.00% |
Special Regulation |
Students must achieve a minimum grade (35%) in both the practical/CA and final examination. |
Continuous Assessment |
Assessment Type |
Assessment Description |
Outcome addressed |
% of total |
Assessment Date |
Examination |
Exam |
1,2,3,4,9 |
10.00 |
n/a |
Examination |
Exam |
1,2,3,4,9 |
10.00 |
n/a |
Practical |
Assessment Type |
Assessment Description |
Outcome addressed |
% of total |
Assessment Date |
Practical/Skills Evaluation |
Practical lab book |
5,6,7,8,10 |
30.00 |
Sem 1 End |
End of Module Formal Examination |
Assessment Type |
Assessment Description |
Outcome addressed |
% of total |
Assessment Date |
Formal Exam |
3 hour exam |
1,2,3,4,7,8,9 |
50.00 |
End-of-Semester |
SETU Carlow Campus reserves the right to alter the nature and timings of assessment
Module Workload
Workload: Full Time |
Workload Type |
Frequency |
Average Weekly Learner Workload |
Lecture |
30 Weeks per Stage |
2.00 |
Laboratory |
30 Weeks per Stage |
1.50 |
Estimated Learner Hours |
30 Weeks per Stage |
2.50 |
Total Hours |
180.00 |
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