Module Title:Molecular Genetics and Immunology 2
Language of Instruction:English
Credits: 5
NFQ Level:8
Module Delivered In 1 programme(s)
Teaching & Learning Strategies: This module will be taught in three theory classes, of one hour each, per week. Timetabling will also accommodate tutorial/practical classes of one hour per week. Relevant class notes, diagrams and self assessment tools will be available at the Institute’s student common drive.
Module Aim: The aim of this module is to give students a functional competency in the theoretical knowledge and the methods of molecular genetics, biotechnology and immunology.
Learning Outcomes
On successful completion of this module the learner should be able to:
LO1 Discuss the mammalian immune response with respect to antibody production and vaccine efficacy.
LO2 Explain the basis of antibody and antigen reactions and demonstrate how this interaction can be commercially exploited.
LO3 Evaluate the production of monoclonal and polyclonal antibodies, their current and potential commercial roles and their industrial, environmental and therapeutic application.
Pre-requisite learning
Module Recommendations

This is prior learning (or a practical skill) that is recommended before enrolment in this module.
No recommendations listed
Incompatible Modules
These are modules which have learning outcomes that are too similar to the learning outcomes of this module.
No incompatible modules listed
Co-requisite Modules
No Co-requisite modules listed
Requirements
This is prior learning (or a practical skill) that is mandatory before enrolment in this module is allowed.
No requirements listed
 

Module Content & Assessment

Indicative Content
Immunology
Mammalian immune response: Overview of the mammalian immune response with respect to antibody production and vaccine efficacy. Antigens and immunogens. Antibody and antigen reactions in vivo and in vitro. Antibody affinity and avidity. Structure and properties of immunoglobulins, overview of main isotypes, source of antibody diversity. Commercial antibody production: Polyclonal and monoclonal antibody production. Large-scale antibody production. Antibody purification methods. Applications of antibody and antigenic reactions, kits, monoclonal antibodies in detection, diagnostics and therapy. Vaccines: Immunization: passive and active. Vaccine production and development with respect to problems associated with human vaccines.
Practical
Practical's will be delivered as tutorials focusing on problem solving and assisting the student in the interpretation and analysis of molecular data generated through modern molecular techniques including; qPCR, Microarray analysis, Southern hybridization analysis, Eliza, Restriction digests, Primer/probe design and optimization, Manipulation of raw sequence data via bioinformatic tools, Sequencing and DNA fingerprinting. Above techniques will be adopted and substituted as appropriate. In addition to the tutorials students will be asked to review, summarise and present key research papers and current developments in topics encountered during the course of study. Material and presentations generated will be assessed on an ongoing basis.
Assessment Breakdown%
Practical40.00%
End of Module Formal Examination60.00%
Special Regulation
Learners are required to achieve a minimum mark (35%) in both practical and Final Exam
No Continuous Assessment
No Project
Practical
Assessment Type Assessment Description Outcome addressed % of total Assessment Date
Practical/Skills Evaluation practical work sheets and paper reviews 1,2,3 40.00 n/a
End of Module Formal Examination
Assessment Type Assessment Description Outcome addressed % of total Assessment Date
Formal Exam Final examination of three hour duration 1,2,3 60.00 End-of-Semester

SETU Carlow Campus reserves the right to alter the nature and timings of assessment

 

Module Workload

Workload: Full Time
Workload Type Frequency Average Weekly Learner Workload
Lecture 12 Weeks per Stage 3.00
Laboratory 12 Weeks per Stage 1.00
Estimated Learner Hours 12 Weeks per Stage 6.42
Total Hours 125.00
 

Module Delivered In

Programme Code Programme Semester Delivery
CW_SABTP_B Bachelor of Science (Honours) in Biosciences with Biopharmaceuticals 8 Mandatory